Synthesis of new triisocyanate curatives 2,2-bis(isocyanatomethyl)propyl isocyanate and 4-(isocyanatomethyl)-1,7-heptyl diisocyanate

Summary Two triisocyanate crosslinking agents were synthesized. The 2,2-bis(isocyanatomethyl)-propyl isocyanate was synthesized from 2,2-bis(hydroxymethyl)propanol in three steps via the triazide and the triamine with an overall yield of 20% and >95% purity as determined by NMR. The 4-(isocyanatomethyl)-1,7-heptyl diisocyanate was synthesized from 1,3,5-pentanetricarboxylic acid in six steps with an overall yield of 23.5% and >98% purity as determined by NMR. This synthesis proceeded via the trimethyl ester, the triol, the tris(p-toluenesulfonate), the triazide and the triamine.