Metalloporphyrin-NO bonding: building bridges with organometallic chemistry |
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Authors: | Ghosh Abhik |
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Affiliation: | Department of Chemistry, University of Troms?, Norway. abhik@chem.uit.no |
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Abstract: | DFT calculations in our laboratory and elsewhere have elucidated fundamental aspects of the structure and bonding of a variety of metalloporphyrin-diatomic complexes, including the biologically important heme CO, NO, and O(2) complexes. We have also studied some more exotic species such as metalloporphyrin-dinitrosyl, -dialkyl, and -diaryl complexes. In the course of this research, we discovered a number of unexpected similarities (isolobal analogies) between the bonding in metalloporphyrin-NO and organometallic compounds. Equally important, DFT calculations have played a significant role in advancing our understanding of selective diatomic ligand binding by heme proteins. |
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