新型电子电离源线型离子阱-飞行时间杂化串联质谱研究进展

本研究介绍了一种新型电子电离源线型离子阱-飞行时间杂化串联质谱仪，该仪器结合了线型离子阱质谱和飞行时间质谱的优点，具有较强的定性分析能力。选用全氟三丁胺(PFTBA)、四氯化碳和丙酮为测试样品对开发的仪器样机进行性能测试，包括对PFTBA碎片离子的离子分离（ISO）和碰撞诱导解离（CID）实验，以及样品同位素离子间的分离实验。测试结果表明，该仪器基本实现了离子碎裂、离子储存和串联质谱分析等功能，能够进行高精度母离子选择。本研究所开发的EI LIT-TOF质谱，在易挥发类有机化合物的结构和化学性质等研究中具有特殊的应用前景。

Development of a Novel Electron Source Linear Ion Trap/Time-of-Flight Hybrid Tandem Mass Spectrometer

This work introduces a novel electron source linear ion trap/time-of-flight hybrid tandem mass spectrometer. The system combine advantages of linear ion trap (LIT) and time-of-flight (TOF) mass spectrometry and it feathers good qualitative abilities. Standard sample of PFTBA, carbon tetrachloride and acetone is used to test the performances. The basic functions including ion trapping, isolation, collision induced dissociation (CID) and LIT-TOF interface has been proved to be excellent. Ion isolation and CID experiment of PFTBA fragment ion are demonstrated. Precise isotope ions isolation experiments shows the good selectivity performance of LIT. The EI LIT-TOF established in our laboratory can be applied to the fields of study the structure and chemical characters of volatile organic compounds (VOCs).