大麻二酚检测方法的研究进展

大麻二酚(cannabidiol,CBD)是一种非精神活性大麻素,不具有成瘾性,并且现代药理学证明,大麻二酚具有诸如抗癫痫、抗焦虑、镇静等多种药理学活性,表明大麻二酚是一种具有广阔应用前景的活性天然产物。工业大麻又名火麻、胡麻、线麻等,为大麻科(Cannabaceae)大麻属(Cannabis)的一年生草本植物。工业大麻应用广泛,作为优质的植物蛋白和植物油脂来源,备受食品加工、保健品、化妆品等行业的青睐。工业大麻在我国使用历史悠久,中国古代医书《黄帝内经》《本草纲目》均有对工业大麻入药的记载。在工业大麻的种植及加工过程中,大麻二酚不断累积和代谢,因此,大麻二酚的检测对工业大麻原料及制品的品质评价及安全控制具有重要意义。本文分类介绍了近年来国内外文献报道的大麻二酚检测方法,对这些方法的应用特点和检测效果进行综述,并对我国未来大麻二酚检测技术的发展趋势进行展望,以期为相关研究提供借鉴。

Research progress on detection methods of cannabidiol

Cannabidiol (CBD) is a non psychoactive cannabinoid without addiction, modern pharmacology has proved that CBD has a variety of pharmacological activities such as anti epilepsy, anti anxiety and sedation, indicating that CBD is an active natural product with broad application prospects. Industrial hemp, also known as hemp, flax, linen hemp, etc., is the panicum miliaceum of Cannabis of Cannabaceae. Industrial hemp is widely used, as a source of high-quality plant protein and vegetable oil, it is favored by food processing, health care products, cosmetics and other industries. Industrial hemp has a long history of use in China, and the ancient Chinese medical books Huangdi neijing and compendium of Materia medica all have records of industrial cannabis used as medicine. CBD accumulates and metabolizes continuously during the planting and processing of industrial cannabis, therefore, the detection of CBD is of great significance to the quality evaluation and safety control of industrial cannabis raw materials and products. This paper introduced the detection methods of CBD reported in the domestic and foreign literature in recent years, summarized the application characteristics and detection effect of these methods, and prospected the development trend of CBD detection technology in the future in China, in order to provide reference for relevant research.