Optimal allocation of bioassays in the case of parametrized covariance functions: an application to Lung’s retention of radioactive particles |
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Authors: | Milan Stehlík Juan M Rodríguez-Díaz Werner G Müller Jesús López-Fidalgo |
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Affiliation: | (1) Department of Applied Statistics, Johannes-Kepler-University, Linz, Austria;(2) Department of Statistics, University of Salamanca, Salamanca, Spain;(3) Department of Mathematics, University of Castilla-La Mancha, Ciudad Real, La Mancha, Spain |
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Abstract: | In this paper, we investigate the effect of employing a parametrized covariance function in a regression experiment on corresponding
optimum designs. We demonstrate these effects in the framework of a real example for measuring the lung’s retention of radioactive
particles. Also, two different covariance functions are considered, and it is shown that this choice can play a crucial role.
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Keywords: | Correlated errors D-optimality Optimal designs Radioactivity retention |
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