双哌嗪盐类化合物电子轰击离子化质谱研究(英文)

对 6个新合成的双哌嗪盐类化合物进行了电子轰击离子化质谱及其裂解规律的研究。研究表明 :通过降低电子轰击电流强度 ,该类化合物的电子轰击离子化质谱的准分子离子和特征碎片峰非常清晰。但 M+和 M2 +离子峰并未出现。在低电子能量条件下 ,发现了 M-2 ]+,M-R]+,M-R-1 ]+,M-2 R]+,甚至 RX]+离子峰的存在。这些现象可能与分子内的 R+重排反应有关。进一步尝试提出该类化合物的电子轰击离子化质谱裂解规律 ,为该类化合物的质谱研究提供有用的信息。

STUDY ON BIS-PIPERAZINIUM SALTS(M2+2Br-2HCl) BY ELECTRON IMPACT IONIZATION MASS SPECTROMETRY

Electron impact ionization mass spectra of six new synthetic bis-piperazinium salts (M2 2Br-2HC1) with anti-tumor activities were obtained. Although the M ions and double charge ions M2 were notobserved in E1 mass spectra, some strange ions such as M-2] ions,M-R] ions , M-R-l] ions, M-2R] ions and even RX] ions presented in EIMS by decreasing the electron energy. These phenomena may be explained as R rearrangement and intermolecular reaction occurring in the condensed phase. We tried to describe the main routes of fragmentation and high sensitive mass spectra of the fragments oaboutthese compounds.