Abstract: | Immunogenetic analysis of Y-factor localization in mouse genome was carried out by means of skin grafts. The data obtained indicate to autosomal localization of Y-factor rather than Y-linked one. This leads to the conclusion that Y-factor is a sex-influenced factor, but not a sex-linked one. If the hypothesis about Y-factor localization in Y-chromosome is accepted, this gene will be identical in CGA and C57B1/6 strains and the variety of reactions, caused by T-antigen, will be determined by the genetical constitution of the male donors and the female recipients. |