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Application of two-dimensional gel-based mass spectrometry to functionally dissect resistance to targeted cancer therapy |
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| Authors: | Oliver Klein Nadine Rohwer Katja Freitag de Molina Stefan Mergler Petra Wessendorf Marion Herrmann Joachim Klose Thorsten Cramer |
| Affiliation: | 1. Berlin-Brandenburg Center for Regenerative Therapies, Charité – Universitätsmedizin Berlin, Berlin, Germany Core Unit Proteomics, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany Institute of Medical and Human Genetics, Charité – Universitätsmedizin Berlin, Berlin, Germany These authors contributed equally to this work.;2. Department of Hepatology and Gastroenterology, Charité – Universitätsmedizin Berlin, Berlin, Germany Molekulares Krebsforschungszentrum (MKFZ), Charité – Universitätsmedizin Berlin, Berlin, Germany These authors contributed equally to this work.;3. German Consortium for Translational Cancer Research (DKTK), Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany;4. Department of Ophthalmology, Charité – Universitätsmedizin Berlin, Berlin, Germany;5. Institute of Medical and Human Genetics, Charité – Universitätsmedizin Berlin, Berlin, Germany;6. Berlin-Brandenburg Center for Regenerative Therapies, Charité – Universitätsmedizin Berlin, Berlin, Germany Core Unit Proteomics, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany Institute of Medical and Human Genetics, Charité – Universitätsmedizin Berlin, Berlin, Germany These authors jointly directed this work. Correspondence: Professor Joachim Klose, Berlin-Brandenburg Center for Regenerative Therapies, Core Unit Proteomics and Institute of Medical and Human Genetics, Charité – Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany E-mail:joachim.klose@charite.de Fax: +49-30-450-566-904;7. Department of Hepatology and Gastroenterology, Charité – Universitätsmedizin Berlin, Berlin, Germany Molekulares Krebsforschungszentrum (MKFZ), Charité – Universitätsmedizin Berlin, Berlin, Germany These authors jointly directed this work. |
| Abstract: | |
| Keywords: | 2DE Gastric cancer HIF-1α Targeted therapy Therapy resistance |