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Advanced Technologies for Engineering Tissue Mimetics
Authors:Tzahi Cohen-Karni  Tal Dvir
Affiliation:1. David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (USA);2. The Laboratory for Tissue Engineering and Regenerative Medicine, Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Science, Tel Aviv University, Tel Aviv 69978 (Israel)
Abstract:Micro- and nanotechnologies have become central to fields ranging from tissue and cellular biophysics to regenerative medicine toward the creation of more complex and progressive tissues. In this article, we overview some of the new technological concepts in this field for recapitulating the native extracellular matrix, designing dynamic microenvironments, and the incorporation of small-scale devices for actuating and monitoring engineered tissue performances.
Keywords:biological activity  medicinal chemistry  molecular devices  nanotechnology  tissue engineering
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