The stress response of critical illness |
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Authors: | J Epstein MJ Breslow |
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Affiliation: | Department of Anesthesiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. |
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Abstract: | The integrated stress response to tissue trauma is crucial for the maintenance of homeostasis. An exaggerated or prolonged response may be detrimental in compromised patients. Knowledge of the involved afferent pathways will suggest therapeutic interventions that may modulate the intensity of the stress response. Described are these concepts as they relate to perioperative medicine. |
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