| 放射自显影海藻酸钙栓塞微球的制备 |
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| 引用本文： | 衣洪福,任东文,包德才,雄鹰,姚文艳,王为,马小军.放射自显影海藻酸钙栓塞微球的制备[J].功能材料,2006,37(12):1988-1990. |
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| 作者姓名： | 衣洪福 任东文 包德才 雄鹰 姚文艳 王为 马小军 |
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| 作者单位： | 中国科学院大连化学物理研究所,生物医学材料工程组,辽宁,大连,116023;中国科学院研究生院,辽宁,大连,116023;中国科学院大连化学物理研究所,生物医学材料工程组,辽宁,大连,116023;中国科学院研究生院,辽宁,大连,116023;渤海大学,化学与化工学院,辽宁,锦州,121000;解放军214医院,辽宁,大连,116000;大连医科大学,辽宁,大连,116023 |
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| 摘 要： | 利用乳化-内部凝胶化法,将放射显影剂碘化油包封于海藻酸钙微球中.通过改变机械搅拌速率可以控制微球的粒径分布.碘化油/海藻酸钙微球可以作为栓塞制剂阻断患处血供,还可以兼具放射自显影的作用,有利于减少碘化油所导致的不良反应,方便治疗.
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| 关 键 词： | 海藻酸钙 微球 放射自显影 |
| 文章编号： | 1001-9731(2006)12-1988-03 |
| 收稿时间： | 2006-07-05 |
| 修稿时间： | 2006-10-07 |
Preparation of autoradiography calcium alginate microspheres |
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| YI Hong-fu,REN Dong-wen,BAO De-cai,XIONG Ying,YAO Wen-yan,WANG Wei,MA Xiao-jun.Preparation of autoradiography calcium alginate microspheres[J].Journal of Functional Materials,2006,37(12):1988-1990. |
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| Authors: | YI Hong-fu REN Dong-wen BAO De-cai XIONG Ying YAO Wen-yan WANG Wei MA Xiao-jun |
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| Affiliation: | 1. Lab. Biomedical Materials Engineering,Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China ; 2. Graduate School of Chinese Academy of Sciences, Chinese Academy of Sciences, Dalian 116023,China 3. College of Chemistry and Chemical Engineering, Bohai University,Jinzhou 121000, China; 4. PLA 214 Hospital, Dalian 116000 ,China; 5. Dalian Medical University,Dalian 116023,China |
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| Abstract: | Calcium alginate microspheres loaded lipoidol were prepared with emulsion-inner gelation, The diameter distribution of the mirospheres was controlled by changing the mechanical rotation rate in the gelation process. The lipoidol/calcium alginate microspheres acted as embolization and autoradiography preparations simultaneously. Lipoidol was loaded in microspheres for stabilization and reducing side effect. |
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| Keywords: | calcium alginate mlcrospheres autoradlography |
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