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Overnight orthokeratology with two brands of reverse-geometry contact lenses
Affiliation:1. Ochsner Clinic Foundation, New Orleans, Louisiana;3. Optum, Inc, Eden Prairie, Minnesota;1. Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland;2. Research Laboratory, Polpharma SA, Pelplińska 19, 80-200 Starogard Gdański, Poland;1. School of Nursing, Chang Gung University of Science and Technology, Taoyuan City, Taiwan, ROC;2. Department of Nursing, Linkou Chang Gung Memorial Hospital, Linkou, Taiwan, ROC;3. Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan, ROC;4. Department of Health Management, I-Shou University, Kaohsiung City, Taiwan, ROC
Abstract:PurposeTo evaluate the refractive and corneal topographical changes of overnight orthokeratology in myopia with two brands of contact lenses.MethodsFourty-four eyes of 22 myopic patients with manifest refraction spherical equivalent (MRSE) of ?1.00 to ?5.00 D (cylinder  ?1.0) were fitted with either DreamLens (Hanita Lenses Investments, Hanita, Israel) (group A) or Rinehart–Reeves (R&R; Danker Laboratories, Sarasota, FL) (group B) reverse-geometry lenses. Each subject eye was evaluated in regards to the uncorrected and corrected distance visual acuities, manifest refraction, slit lamp biomicroscopy, and corneal topography at each follow-up examination.ResultsThe follow-up was 1 year. For groups A and B, the mean uncorrected distance visual acuity was ?0.02 ± 0.10 log MAR (20/20) and ?0.08 ± 0.12 log MAR (20/20) respectively at year-1 examination. The mean MRSE decreased from ?2.70 ± 0.9 D to ?0.50 ± 0.08 D in group A and ?3.1 ± 1.1 to ?0.62 ± 0.18 D in group B at week-1; and remained stable thereafter in each group. For both groups, starting with week-1, the mean anterior best-fit sphere (ABFS) was statistically significantly flatter from baseline. A high correlation was found between the change in apical corneal power (ACP) and MRSE (r1 = 0.79, r2 = 0.71), and there was a good correlation between the change in ABFS and MRSE (r1 = 0.67, r2 = 0.64) in both groups. No significant ocular adverse events were observed during study.ConclusionsBoth types of contact lenses safely and effectively decreased the myopic refractive error at 1 year follow-up. The refractive effect was mainly induced by the changes in the anterior corneal shape and the ACP.
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