Measurement of neutron dose equivalent to proton therapy patients outside of the proton radiation field |
| |
| Affiliation: | 1. Harvard Cyclotron Laboratory, 44 Oxford Street, Cambridge, MA 02138, USA;2. Massachusetts General Hospital, 55 Fruit Street, NPT-100, Boston, MA, USA;1. Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Pôle Radioprotection de l''Homme, External Dosimetry Department, BP17, 92260 Fontenay-aux-Roses, France;2. Institut Curie – Centre de Protonthérapie d''Orsay (CPO), Campus Universitaire Bâtiment 101, 91898 Orsay, France;1. Department of Medical Physics, Austin Health, Victoria, Australia;2. School of Physical Sciences, University of Adelaide, South Australia, Australia;3. Department of Medical Physics, GenesisCare, South Australia, Australia;1. Department of Nuclear Engineering, Hanyang University, 222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, South Korea;2. Neutron Utilization Technology Division, Korea Atomic Energy Research Institute, Daejeon, 34129, South Korea;3. Proton Therapy Center, National Cancer Center, Goyang-si, Gyonggi-do 10408, South Korea;4. IT Convergence Technology Research Laboratory, Electronics and Telecommunications Research Institute, Daejeon, 34129, South Korea;1. Department of Oncology, KU Leuven, Leuven, Belgium;2. Department of Gynecologic Oncology, Netherlands Cancer Institute and Amsterdam University Medical Center, Amsterdam, the Netherlands;3. Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands;4. Department of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium;5. Department of Pathology and Medical Biology, Pathology Section, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands;6. Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands;7. Department of Medical Oncology, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands;8. Department of Medical Oncology, Netherlands Cancer Institute and Amsterdam University Medical Center, Amsterdam, the Netherlands;9. Department of Gynecologic Oncology, University Hospitals Leuven, Leuven, Belgium;10. Department of Obstetrics and Gynecology, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands |
| |
| Abstract: | Measurements of neutron dose equivalent values and neutron spectral fluences close to but outside of the therapeutic proton radiation field are presented. The neutron spectral fluences were determined at five locations with Bonner sphere measurements and established by unfolding techniques. More than 50 additional neutron dose equivalent values were measured with LiI and BF3 thermal neutron detectors surrounded by a 25 cm polyethylene moderating sphere. For a large-field treatment, typical values of neutron dose equivalent per therapeutic proton absorbed dose, H/D, at 50 cm distance from isocenter, range from 1 mSv/Gy (at 0° with respect to the proton beam axis) to 5 mSv/Gy (at 90°). Experiments reveal that H/D varies significantly with the treatment technique, e.g., patient orientation, proton beam energy, and range-modulation. The relative uncertainty in H/D values is approximately 40% (one standard deviation). |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
