| 泛醌（辅酶Q10）的合成研究 |
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| 引用本文： | 潘仙华,毛海舫,吴晓. 泛醌（辅酶Q10）的合成研究[J]. 香料香精化妆品, 2006, 0(5): 1-4 |
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| 作者姓名： | 潘仙华 毛海舫 吴晓 |
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| 作者单位： | 1. 上海应用技术学院,生物与食品工程系;凯美联合科教实验室,上海,200235
2. 凯美联合科教实验室,上海,200235 |
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| 摘 要： | 本文报道了一种化学合成泛醌(辅酶Q10)的简捷方法,以茄呢醇为原料,经溴化、缩合、水解和加成反应得到合成泛醌(辅酶Q10)的关键中间体--4-十异戊烯基-3-羟基-3-甲基-1-丁烯.该化合物再和2, 3-二甲氧基-5-甲基-1,4-苯醌偶联后得到泛醌(辅酶Q10).
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| 关 键 词： | 泛醌(辅酶Q10) 茄呢醇 合成 |
| 修稿时间： | 2006-08-04 |
Study on the Synthesis of Ubiquinone (CoQ10) |
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| Pan Xianhua,Mao Haifang,Wu Xiao. Study on the Synthesis of Ubiquinone (CoQ10)[J]. Flavour Fragrance Cosmetics, 2006, 0(5): 1-4 |
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| Authors: | Pan Xianhua Mao Haifang Wu Xiao |
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| Abstract: | A concise synthetic method of Ubiquinone (CoQ10) was reported in this paper. 4-Decaprenyl-3-hydroxy-3-methyl-1-butene, a key intermediate for Ubiquinone (CoQ10), was prepared from solanesol via bromization, coupling, hydrolyzation and additional reaction. Finally, the pure CoQ10 was obtained by the coupling of 4-Decaprenyl-3-hydroxy-3-methyl-1-butene with 2, 3-dimethoxyl-5-methyl-1,4-benzoquinone. |
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| Keywords: | Ubiquinone (CoQ10) Solanesol Synthesis |
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