| 冰岛参对小鼠肠道粘膜SIgA分泌的影响 |
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| 引用本文： | 左涛,律迎春,曹露,唐庆娟,王静凤,薛长湖,张彩欣. 冰岛参对小鼠肠道粘膜SIgA分泌的影响[J]. 食品工业科技, 2012, 0(1): 373-375 |
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| 作者姓名： | 左涛 律迎春 曹露 唐庆娟 王静凤 薛长湖 张彩欣 |
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| 作者单位： | 1. 中国海洋大学食品科学与工程学院,山东青岛,266003
2. 青岛市市立医院病理科,山东青岛,266003 |
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| 基金项目： | 海洋公益性行业科研专项(201105029);国家自然科学基金(31071525) |
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| 摘 要： | 目的:探讨冰岛参(Cucumaria frondosa)对小鼠肠道粘膜SIgA分泌的影响。方法:将50只Balb/c小鼠随机分为5组:正常组、模型组、低剂量组、中剂量组、高剂量组。采用环磷酰胺诱导免疫低下模型,取小鼠肠道进行组织学观察、检测肠粘膜SIgA的含量,观察冰岛参对肠道粘膜免疫的保护作用。结果:与模型组相比,低剂量冰岛参摄入能促进肠粘膜SIgA的分泌,对小肠绒毛有一定的保护作用。结论:低剂量冰岛参摄入量能够明显保护小鼠肠粘膜,促进SIgA的分泌,对肠炎有一定的防治作用。
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| 关 键 词： | 冰岛参 体重 小肠绒毛 SIgA Balb/c小鼠 |
Promotion effect of Cucumaria frondosa on the secretion of mice intestinal SIgA |
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| ZUO Tao,LV Ying-chun,CAO Lu,TANG Qing-juan,WANG Jing-feng,XUE Chang-hu,ZHANG Cai-xin. Promotion effect of Cucumaria frondosa on the secretion of mice intestinal SIgA[J]. Science and Technology of Food Industry, 2012, 0(1): 373-375 |
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| Authors: | ZUO Tao LV Ying-chun CAO Lu TANG Qing-juan WANG Jing-feng XUE Chang-hu ZHANG Cai-xin |
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| Affiliation: | 1.College of Food Science and Engineering,Ocean University of China,Qingdao 266003,China;2.Qingdao Municipal Hospital,Department of Pathology,Qingdao 266003,China) |
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| Abstract: | Purpose:Investigate the effect of Cucumaria frondosa on the secretion of mice intestinal SIgA.Methods:Fifty mice were randomly divided into 5 groups:normal group,model group,low dose group,medium dose group,high dose group.Used models of low-immunity mice induced by injected cyclophosphamide,detect SIgA content and histological observation of ileum.Results:Compared with model group,low dose Cucumaria frondosa could have remarkable effect of protecting intestinal villi,and the amount of SIgA secretion.Conclusions:Cucumaria frondosa can enhance the amount of intestinal SIgA,and thus protect intestinal villi from hurting,which makes it a good material to prevent enteritis. |
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| Keywords: | Cucumaria frondosa bodyweight intestinal villi SIgA Balb/c mouse |
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