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酸奶中乳酸菌的药物敏感性分析
引用本文:周宁,魏新元,所辰宇,张建新.酸奶中乳酸菌的药物敏感性分析[J].食品工业科技,2012(2):130-133.
作者姓名:周宁  魏新元  所辰宇  张建新
作者单位:西北农林科技大学食品科学与工程学院,陕西杨凌,712100
基金项目:高等学校博士点科研基金项目(20090204120028)
摘    要:目的:分析和鉴定不同产地酸奶中乳酸菌对一些常用抗生素的敏感性,指导合理使用抗菌药物与合理使用乳酸菌发酵制品。方法:利用改良的MRS培养基从各地酸奶中分离获得乳酸菌,然后采用琼脂稀释法,对分离获得的18株保加利亚乳杆菌和28株嗜热链球菌对11种常用抗生素的药物敏感性进行检测和分析。结果:同一菌株对不同的抗生素具有不同的药物敏感性,不同菌株对同一种抗生素也显示出不同的敏感性。结论:乳酸菌对常用抗生素的多重耐药已成为普遍现象,不同来源的菌株表现出了不同的耐药性。

关 键 词:乳酸菌  药物敏感性  琼脂稀释法  抗生素  最低抑菌浓度

Antimicrobial susceptibility testing of lactic acid bacteriaisolated from yoghurts
ZHOU Ning,WEI Xin-yuan,SUO Chen-yu,ZHANG Jian-xin.Antimicrobial susceptibility testing of lactic acid bacteriaisolated from yoghurts[J].Science and Technology of Food Industry,2012(2):130-133.
Authors:ZHOU Ning  WEI Xin-yuan  SUO Chen-yu  ZHANG Jian-xin
Affiliation:*(College of Food Science and Engineering,Northwest A & F University,Yangling 712100,China)
Abstract:Objective:To investigate the susceptibility of lactic acid bacteria(LAB)isolated from yoghurts for medical purpose to 11 antimicrobial agents.Methods:18 Lactobacillus bulgaricus and 28 Streptococcus thermophilus selected on modified MRS media from yoghurts were examined for antibiotic resistance by using the agar dilution method.Results:The same strain presented different sensitivity to different antibiotics,and different isolates also showed different resistance to the same antibiotic.Conclusions:Multidrug resistance was identified in most isolates and different resistance was seen in different isolates.
Keywords:lactic acid bacteria  antimicrobial susceptibility  agar dilution method  antibiotics  minimum inhibitory concentration
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