Electrospinning of collagen-chitosan complex |
| |
Authors: | Zonggang Chen Xiumei Mo Fengling Qing |
| |
Affiliation: | a Institute of Biological Science and Biotechnology, Donghua University, Shanghai, 201620, China b College of Chemistry and Chemical Engineering, Donghua University, Shanghai, 201620, China |
| |
Abstract: | The collagen-chitosan complex nanofibers have been prepared for the first time by electrospinning. The mixed HFP/TFA (the volume ratio of 90/10) was found to be the appropriate solvent for electrospinning. The concentration of the spinning solution and the ratio of chitosan/collagen were varied and adjusted to get smooth nanofibers. It was found that the diameter of the spun fibers became thick with the concentration of the solution increasing and became fine with the ratio of the chitosan/collagen increasing. We have characterised the molecular interactions in collagen-chitosan complex by Fourier transform infrared spectroscopy. The spun fibers are designed to mimic the native extracellular matrix for tissue engineering and to develop functional biomaterials. |
| |
Keywords: | Collagen Chitosan Electrospinning Nanofiber Biomaterials |
本文献已被 ScienceDirect 等数据库收录! |