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Creep of the eye sclera
Authors:E. D. Shchukin  Victoria N. Izmailova  Natalia I. Larionova  Michael M. Krasnov  Alexandr N. Gurov  Anatoly I. Bessonov  Galina N. Afanas’eva
Affiliation:(1) Department of Colloid Chemistry, Moscow State University, Moscow 119899, Russia (September till December) and also Department of Geography and Environmental Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA (January till August) Fax: +7-095-932-8846, e-mail: shchukin@izm.chem.msu.su, RU;(2) Department of Colloid Chemistry, Moscow State University, Moscow 119899, Russia, RU;(3) Research Institute of Eye Diseases, Russian Academy of Medical Sciences, ul. Rossolimo 11, Moscow 111902, Russia, RU;(4) Institute of Physical Chemistry, Russian Academy of Sciences, Leninsky pr. 31, Moscow 117915, Russia, RU
Abstract: Irreversible stretching (creep) of the eye sclera, considered as a cause of the high myopia, has been studied experimentally. Both dramatic acceleration and significant deceleration of the sclera creep have been observed in the presence of some enzymes. Creep of various connective tissues caused by static and cyclic mechanical stresses (gravity, blood pressure, etc.) can manifest in many age and pathological changes in human body. Authors express the hope that investigations in this area and finding appropriate inhibitors may replace surgery (eye, cosmetic) by prophylactic therapy. Received: 21 July 1998 / Accepted: 28 August 1998
Keywords:  Myopia  Creep of sclera  Enzymes  Creep of connective tissues
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