首页 | 本学科首页   官方微博 | 高级检索  
     


Fabrication of MgAl2O4 Spinel Scaffolds and Sonochemical Synthesis and Deposition of Hydroxyapatite Nanorods
Authors:Anu Sharma  Manu Krishnan  Roy Johnson  Mantravadi Krishna Mohan
Affiliation:1. Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi, India;2. International Advanced Research Centre for Powder Metallurgy and New materials (ARCI), Hyderabad, India;3. National Institute of Technology, Warangal, India
Abstract:Hydroxyapatite (HAp) is one of the most emerging biocompatible ceramic widely used as scaffolds in various biomedical applications such as orthopedics and dentistry. In spite of the superior properties for biomedical applications, they exhibit poor mechanical properties. This has lead to the concept of fabricating composite out of bioactive and bioinert material to derive bioactivity in combination with desirable mechanical properties. In this study, bioinert magnesium aluminate (MgAl2O4) spinel scaffolds are prepared through polymeric foam replication process followed by sintering. Sintered foams have exhibited good structural integrity and the stress–strain curves recorded during the uniaxial compression have shown a plateau indicating high‐energy absorption capability. Sonochemical process has been employed for the simultaneous synthesis and deposition of HAp formulation from the stoichiometric solution of precursors on the spinel scaffolds. Sonochemical process has resulted in the formation of phase pure HAp with unique morphology of nanorods coated throughout the three‐dimensional foam structures. Cytotoxicity evaluation of this new scaffold material has not shown any alteration in the viability, growth, and morphology of the cells. The new scaffold material thus developed is expected to have high potential for biomedical applications.
Keywords:
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号