Microstructure,biodegradation, antibacterial and mechanical properties of ZK60-Cu alloys prepared by selective laser melting technique |
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| Authors: | Cijun Shuai Long Liu Mingchun Zhao Pei Feng Youwen Yang Wang Guo Chengde Gao Fulai Yuan |
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| Affiliation: | 1. State Key Laboratory of High Performance Complex Manufacturing, College of Mechanical and Electrical Engineering, Central South University, Changsha 410083, China;2. Jiangxi University of Science and Technology, Ganzhou 341000, China;3. Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China;4. School of Material Science and Engineering, Central South University, Changsha 410083, China;5. Health Management Center, Xiangya Hospital, Central South University, Changsha 410008, China |
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| Abstract: | Magnesium (Mg) alloys are receiving increasing attention for body implants owing to their good biocompatibility and biodegradability. However, they often suffer from bacterial infections on account of their insufficient antibacterial ability. In this study, ZK60-xCu (x?=?0, 0.2, 0.4, 0.6 and 0.8?wt%) alloys were prepared by selective laser melting (SLM) with alloying copper (Cu) to enhance their antibacterial ability. Results showed that ZK60-Cu alloys exhibited strong antibacterial ability due to combination of release of Cu ions and alkaline environment which could kill bacteria by destroying cellular membrane structure, denaturing enzymes and inhibiting deoxyribonucleic acid (DNA) replication. In addition, their compressive strength increased due to grain refinement and uniformly dispersing of short-bar shaped MgZnCu phases. Moreover, ZK60-Cu alloys also exhibited good cytocompatibility. In summary, ZK60-Cu alloys with antibacterial ability may be promising implants for biomedical applications. |
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| Keywords: | Magnesium alloys Copper Antibacterial ability Cytocompatibility Mechanical properties |
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