Together wherever we go: the ethnographic child and the developmentalist |
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Authors: | J Lucariello |
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Affiliation: | Second Department of Medicine, Kurume University School of Medicine, Asahi-machi 67, Kurume-shi, Fukuoka, 830, Japan. |
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Abstract: | We demonstrated immunohistochemical staining of a-fetoprotein (AFP) in small hepatocellular carcinoma (HCC). Fifty-six patients with HCC less than 2 cm in diameter were studied. Twenty-five HCCs (44.6%) were positive for AFP-staining. The positive rate of AFP-staining in HCC tissue was higher in the patients with serum AFP concentration above 20 ng/ml than that of the patients with below 20 ng/ml. AFP-staining was demonstrated on the rough endoplasmic reticulum of HCC cells by immuno-electron microscopy. AFP-staining of tissue specimens obtained by fine needle biopsy is useful in the histologic diagnosis of HCC. |
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