A membrane for removing endotoxins from aqueous solutions |
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| Authors: | Narbik A Karamian Paul F Waters |
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| Affiliation: | National Institutes of Health, Division of Research Services Branch, Bethesda Md 200(H)14 U.S.A.;Department of Chemistry, The American University, Washington, D.C. 20016 U.S.A. |
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| Abstract: | Membranes made from solutions of 18 wt.% cellulose acetate, 58 wt.% 1,4-dioxane and 24 wt.% water reject 98.5% of the endotoxins from aqueous solutions containing ppm levels of the contaminant in a single pass at operating pressures of 3.52 kg/cm2 ( ～ 50 psi). These membranes exhibited an average flux of 30.7 × 10-2 cc/cm2-min (108.5 gal/ft2-day) under these conditions. The effects of the following variables at room temperature are examined: casting solution composition, temperature and composition of quenching medium, membrane thickness and percolating time. |
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