| 新型医用粘合剂:α-氰基丙烯酸1,2-异丙叉甘油酯的合成 |
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| 引用本文： | 曾国蓉 冯地旺. 新型医用粘合剂:α-氰基丙烯酸1,2-异丙叉甘油酯的合成[J]. 中国胶粘剂, 1993, 2(1): 20-21 |
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| 作者姓名： | 曾国蓉 冯地旺 |
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| 作者单位： | 西南师范大学化学系，西南师范大学化学系，西南师范大学化学系，西南师范大学化学系，西南师范大学化学系，西南师范大学化学系 |
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| 摘 要： | α-氰基丙烯酸-1,2-异丙叉甘油酯是一种新型的医用快速生物降解的组织粘合剂和止血剂。本文改进了合成工艺,提高到产率41～51％,本工艺具有条件温和,反应速度快和后处理简单的优点。经动物试验证明其止血效果优于目前临床上常用止血药物。
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| 关 键 词： | α-氰基丙烯酸-1 2-异丙叉甘油酯 组织粘合剂 止血剂 |
Synthesis of A New Medicinal Adhesive-1,2-Isopropylidene Glyceryl-α-Cyanoacrylate |
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| Zeng Guorong Feng Diwang Deng Dexian Yi Xin Zhou Chengbang Yang Xuelin. Synthesis of A New Medicinal Adhesive-1,2-Isopropylidene Glyceryl-α-Cyanoacrylate[J]. China Adhesives, 1993, 2(1): 20-21 |
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| Authors: | Zeng Guorong Feng Diwang Deng Dexian Yi Xin Zhou Chengbang Yang Xuelin |
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| Abstract: | 1,2-Isopropylidene glyceryl-a-cyanoacrylate (CAG) is a new medicinal tissue adhesive and hemostatic agent which can biodegrade rapidly. Apart from increasing the yield up to 41-51%, the improved synthesis technology introduced in this paper has many other advantages such as moderate reaction, high reaction speed and simple aftertreatment. It is proved that its hemostatic efficacy is better than the usual clinical hemostatic agent. |
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| Keywords: | 1 2-Isopropylidene glyceryl-α-cyanoacrylate tissue adhesive hemostatio agent |
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