沉淀法制备硅酸钙及其体外生物活性的研究

采用沉淀法制备的硅酸钙粉体经成型,在1200℃下常压烧结,制备出高纯的硅酸钙陶瓷,通过模拟体液浸泡对其体外生物活性进行了研究。X射线衍射(XRD)和扫描电镜(SEM)的结果表明:在1200℃下烧结制得的硅酸钙陶瓷主晶相为β型硅酸钙(-βCS);在模拟体液中浸泡14d后其表面可见类骨羟基磷灰石生成,28d后生成大量羟基磷灰石。因此,沉淀法合成的硅酸钙具有良好的诱导类骨羟基磷灰石形成能力和体外生物活性。

In Vitro Bioactivity of Calcium Silicate Prepared by a Precipitation Method

The high-purity calcium silicate ceramics were sintered at 1200℃ under the atmospheric pressure with the calcium silicate powder synthesized by the precipitation method. The in-vitro bioactivity of the prepared samples was evaluated by investigating their bone-like apatite-formation ability in simulated body fluid （SBF）. The calcium silicate ceramics were characterized by X-ray diffraction （XRD） and scanning e- lectron microscopy （SEM）. The results show that the prepared sample is mainly constituted by the β-calcium silicate （β-CS）. The bone-like hydroxyapatite （HAp） is formed on the surface of the calcium silicate ceramics after 14-day soaking in SBF, and more bone-like HAp formed after 28-day soaking, which indicate good in-vitro bioactivity.