| 灵芝生物转化蛋白核小球藻发酵粗多糖的抑瘤实验 |
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| 引用本文： | 杨从发,丁重阳,章克昌.灵芝生物转化蛋白核小球藻发酵粗多糖的抑瘤实验[J].中国酿造,2009(5). |
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| 作者姓名： | 杨从发 丁重阳 章克昌 |
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| 作者单位： | 1. 江南大学,工业生物技术教育部重点实验室,江苏,无锡,214122;淮海工学院,海洋学院,江苏,连云港,222000
2. 江南大学,工业生物技术教育部重点实验室,江苏,无锡,214122 |
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| 摘 要： | 在灵芝基础培养基中添加小球藻粉，灵芝能对小球藻细胞进行生物破壁，同时进行牛物转化：藻粉添加量以10g／L为最佳，产生的多糖最高达0．29mg／L。提取转化的多糖，并与灵芝多糖、小球藻提取多糖的混合物进行抗肿瘤实验：结果表明，产生的转化多糖抗肿瘤效果最好，仡最适剂量（0．2g／kg·d）时，抑瘤率为76．2％。
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| 关 键 词： | 灵芝 蛋白核小球藻 多糖 抗肿瘤 |
Anti-tumor effect of polysaccharides from ferment liquid of bioconverted Chlorella pyrenoidosa by Ganoderma lucidum |
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| YANG Congfa,Ding Zhongyang,ZHANG Kechang.Anti-tumor effect of polysaccharides from ferment liquid of bioconverted Chlorella pyrenoidosa by Ganoderma lucidum[J].China Brewing,2009(5). |
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| Authors: | YANG Congfa Ding Zhongyang ZHANG Kechang |
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| Abstract: | Appending Chlorella pyrenoidosa powder by 10g/L in the basic medium of Ganoderma lucidum could enhance the polysaccharides yield to 0. 29mg/L by bioconversion. In order to study the anti-tumor activity of different polysaccharides (from fermentation liquid of bioconverted Chlorella pyrenoidosa by Ganoderma lucidum, from fermentation liquid of Ganoderma lucidum in basic madium, from Chlorella pyrenoidosa, or mixed polysaccharides), an experiment was carried out in vivo. The results showed the bioconverted polysaccharides had the best anti-tumor activity. The anti-tumor inhibition was 76. 2% at the optimum |
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| Keywords: | Ganoderma lucidum Chlorella pyrenoidosa polysaccharides anti-tumor |
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