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酒精性肝病发病机制及防治机理研究
引用本文:陈湘宁,郭琳博,李宇华,胡婉珊,丁轲. 酒精性肝病发病机制及防治机理研究[J]. 食品与机械, 2011, 27(6)
作者姓名:陈湘宁  郭琳博  李宇华  胡婉珊  丁轲
作者单位:北京农学院食品科学学院,北京,102206
基金项目:北京市中青年骨干教师项目(编号:PHR201008416); 2011年北京市优秀人才项目(编号:2010D005021000002); 农产品有害微生物及农残检测与控制北京市重点实验室项目(编号:ZC2011001)
摘    要:长期过量饮酒会造成人体多器官损伤,尤其对肝脏损伤尤为严重.ALD的发病机制较为复杂,文章从乙醇在人体内的代谢途径及其在肝脏中主要酶系统的代谢机制,对酒精性肝病的发病机制及解酒护肝作用机理进行详尽的阐述.

关 键 词:乙醇代谢  酒精性肝病  解酒护肝  机制

Research progress on pathogenesis of alcoholic liver diseases and mechanism of its prevention and treatment
CHEN Xiang-ning , GUO Lin-bo , LI Yu-hua , HU Wan-shan , DING Ke. Research progress on pathogenesis of alcoholic liver diseases and mechanism of its prevention and treatment[J]. Food and Machinery, 2011, 27(6)
Authors:CHEN Xiang-ning    GUO Lin-bo    LI Yu-hua    HU Wan-shan    DING Ke
Affiliation:CHEN Xiang-ning GUO Lin-bo LI Yu-hua HU Wan-shan DING Ke(Faculty of Food Science,Beijing University of Agriculture,Beijing 102206,China)
Abstract:Excessive drinking for a long time can induce damage to many organs,especially to the liver.The pathogenesis of ALD is complicated.Based on the metabolism pathway of ethanol through the human body and three main enzyme systems in the liver,elaborated on the pathogenesis of the alcoholic liver disease and the mechanism of relieving alcoholism and liver protection.
Keywords:ethanol metabolism  alcoholic liver disease  relieving alcoholism and liver protection  mechanism  
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