Optimizing nanoencapsulation of Heracleum lasiopetalum by response surface methodology |
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Authors: | Mahsa Yazdan-Bakhsh Mojtaba Nasr-Esfahani Reza Esmaeilzadeh Kenari Mohammad Fazel-Najafabadi |
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Affiliation: | 1. Department of Food Science and Technology, Najafabad Branch, Islamic Azad University, Najafabad, Iran;2. Department of Chemistry, Najafabad Branch, Islamic Azad University, Najafabad, Iran;3. Department of Food Science and Technology, Sari Agricultural Sciences and Natural Resources University (SANRU), Sari, Iran;4. Department of Food Science and Technology, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran |
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Abstract: | This study was carried out to optimize formulation for Heracleum lasiopetalum (golpar) extract nanoencapsulation by response surface methodology (RSM). The primary water-in-oil emulsion was fabricated by (5%–10%) golpar extract (GE), (40%–35%) emulsifier span 80 (EM), and (50%–60%) sunflower oil (SO). The coating materials were the mixture of Lepidium sativum seed gum (LSG) and whey protein concentrate (WPC) at different ratios (1:0, 1:1, and 0:1). The yield of nanoencapsulation of GE, particle size, and zeta potential was investigated as responses of RSM. The optimal formulation for water-in-oil-in-water emulsion of GE were SO: 50.46%, GE 9.52%, and EM: 36.30% in LSG, SO: 57.07%, GE: 7.12%, and EM: 30.85% in LSG:WPC, and SO: 54.98%, GE: 9.05%, and EM: 39.87% in WPC coating. In conclusion, the nanoencapsulation of GE prepared with the optimized formulation by RSM ensures the gradual release and higher stability to sedimentation during storage with nanometric size and high yield of encapsulation. The nanocapsules of GE can be used as a natural antioxidant in food systems. |
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Keywords: | golpar extract nanoencapsulation optimized formulation response surface methodology |
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