乙烯基胶原蛋白微球的制备及其应用

为了得到带有“-C=C-”的胶原蛋白微球,我们使用甲基丙烯酸酐对胶原蛋白改性,再采用乳化交联法将改性胶原蛋白制备成乙烯基胶原蛋白微球(CMAs),并将微球应用到尼龙基材上。研究了CMAs的制备条件,使用傅里叶红外光谱(FT-IR)、扫描电子显微镜(SEM)、激光粒度分析仪等对CMAs和乙烯基胶原蛋白微球/尼龙(Nylon-CMAs)进行表征。结果表明,当乙烯基胶原蛋白浓度为15%,转速为800 r/min,交联剂用量为0.8 mL,水油体积比为1∶5,乳化剂用量为2%时,制备的乙烯基胶原蛋白微球的平均粒径为21.204μm,形貌规整、圆整度好,表面光滑,粒径分布较窄。接触角结果显示将微球修饰到尼龙上可以使尼龙由原来的疏水织物变为亲水织物,且制备的织物具有较好的水热稳定性能。

Preparation and application of vinyl collagen microspheres

In order to obtain the collagen microspheres with“-C=C-”,the collagen was modified by methacrylate anhydride,and then the modified collagen was prepared into vinyl collagen microspheres(CMAs)by the emulsion-crosslinking method and the microspheres were applied to nylon substrate.The preparation conditions of CMAs were studied.The vinyl-collagen microspheres and vinyl-collagen microspheres/nylon were characterized by the Fourier infrared spectrum(FT-IR),scanning electron microscopy(SEM)and laser particle sizer.The results show that when the concentration of vinyl collagen was 15%,the stirring speed was 800 r/min,the dosage of cross-linking agent was 0.8 mL,the water/oil ratio was 1∶5,and the emulsifier dosage was 2%,the average particle size of CMAs was 21.204μm,and had regular morphology,good roundness,smooth surface.The contact Angle results show that the nylon modified with microspheres can change from hydrophobic fabric to hydrophilic fabric,and the prepared fabric had better hydrothermal stability.