| 新型钙离子拮抗剂尼伐地平 |
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| 引用本文： | 常宏宏,魏文珑.新型钙离子拮抗剂尼伐地平[J].精细与专用化学品,2003,11(20):25-27. |
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| 作者姓名： | 常宏宏 魏文珑 |
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| 作者单位： | 太原理工大学化学与技术工程学院 |
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| 摘 要： | 尼伐地平属于第二代二氢吡啶类钙离子拮抗剂 ,其与Ca2 + 通道特异部位的结合力比硝苯地平强 10倍 ,作用持续时间较之长 2～ 3倍 ,血药浓度较为平稳 ,良好的降压作用能维持 2 4h以上。因此 ,尼伐地平是安全、有效的首选高血压治疗药物 ,其应用前景十分广阔 ,市场潜力十分巨大。
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| 关 键 词： | 尼伐地平 钙离子拮抗剂 高血压 |
Nilvadipine a New Calcium Ion Antagonist |
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| Chang Honghong,Wei Wenlong.Nilvadipine a New Calcium Ion Antagonist[J].Fine and Specialty Chemicals,2003,11(20):25-27. |
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| Authors: | Chang Honghong Wei Wenlong |
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| Affiliation: | Chang Honghong Wei Wenlong |
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| Abstract: | Nilvadipine is the second generation of dihydropyridine calcium ion antagonist. Its cohesion with the special location of calcium ion is 10 times stronger than previous Nifedipine with lasting 2 to 3 times longer. The blood pressure decreasing effect can be maintained well for 24 hours because of its steady pharmaceutical concentration in blood. So Nilvadipine is a safe, efficacious and first-selective pharmaceutical in treatment of hypertension. Hence it has a wild potential in the market. |
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| Keywords: | Nilvadipine calcium ion antagonist hypertension |
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