Comparative Study of the Micellar and Antimicrobial Activity of Gemini-Conventional Surfactants in Pure and Mixed Micelles |
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Authors: | Mohmad S Sheikh Ahmad J Khanam Rayees-ul H Matto Kabir-ud-Din |
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Affiliation: | 1. Aligarh, India
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Abstract: | We have carried out mixed micellization of pentanediyl-α,ω-bis(dimethyl cetylammonium bromide) (G5) with conventional cationic cetylpyridinium chloride (CPC) and nonionic polyoxyethylene (20) cetyl ether (C16E20) in aqueous media and explored their antimicrobial activity in single and binary systems against Escherichia coli (E.coli), Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus). The compounds tested showed excellent antibacterial activity: 0.76–3.38 g/l minimum inhibitory concentration (MIC) and were more active against gram +ve bacteria. For surfactant mixtures G5-C16E20 > G5-CPC, the ionic-nonionic binary surfactant showed greater antibacterial activity. The experimental results of this study may be profitably used to understand and predict the antibacterial activity of gemini-conventional surfactant systems and provide valuable information for selection of surfactant for microbiocidal action. |
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Keywords: | CMC Mixed micellization Nonionic Cationic Gemini surfactant Minimum inhibitory concentration Antimicrobial activity |
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