纳米羟基磷灰石/聚酰胺多孔支架材料的制备及性能研究

使用多种致孔剂采用粒子沥滤法制备了纳米羟基磷灰石／聚酰胺多孔支架材料，用IR、XRD、SEM等手段对多孔复合材料的组成结构及形貌进行了表征，并检测了其物理性能指标。结果表明，复合材料中两相分散均匀，且发生了界面结合；材料的孔隙率与致孔剂的含量成正比，支架中大孔与微孔并存且相互贯通；以NaCl作致孔剂且孔隙率达到80％左右时的支架材料可以同时满足组织工程对孔隙率和力学强度的双重要求。

The Preparation and Investigation of Porous Nano-hydroxyapatite/Polyamide Scaffolds

Porous n-HA/PA66 scaffolds were fabricated with different porogens through the particulate-leaching technique. The structure and morphology were studied by IR, XRD and SEM, and the physical properties were also tested. The results indicated that the two phases in the composite dispersed uniformly and bonded each other strongly. The porosity is proportional to the content of porogens, and macropores and micropores coexist and interconnect in the scaffolds. When the porosity is up to 80%, the porosity and the mechanical strength of the scaffolds prepared can meet the demands of tissue engineering at the same time.