| 广藿香酮膜剂处方筛选研究 |
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| 引用本文： | 邹玉繁,汪小根.广藿香酮膜剂处方筛选研究[J].广东化工,2014(15):105-106. |
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| 作者姓名： | 邹玉繁 汪小根 |
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| 作者单位： | 广东食品药品职业学院,广东广州510520 |
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| 基金项目： | 广东省卫生基金资助项目（A2011143）;广东省自然科学基金（9151052005000003）;2013年广东省高等学校第七批“千百十工程”人才培养专题项目 |
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| 摘 要： | 目的筛选广藿香酮膜剂处方的最佳组成。方法以溶解度、柔韧性为考察指标筛选膜材种类和增塑剂用量,采用均匀设计法,以泛油程度为指标进行关联度分析,确定促进剂的用量。结果最佳膜材为PVA1,加入5%甘油,5%吐温-80,透皮吸收促进剂最优组合为氮酮∶油酸∶丙二醇=6%∶5%∶6%。结论本实验方法优选广藿香酮膜剂的处方,处方效果满意。
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| 关 键 词： | 广藿香酮膜剂 处方优选 膜材 增塑剂 促进剂 均匀设计 |
Study on the Optimization of the Formulation of Pogostone Film |
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| Zou Yufan,Wang Xiaogen.Study on the Optimization of the Formulation of Pogostone Film[J].Guangdong Chemical Industry,2014(15):105-106. |
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| Authors: | Zou Yufan Wang Xiaogen |
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| Affiliation: | (Guang Dong Food and Drug Vocational College, Guangzhou 510520, China) |
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| Abstract: | Objective To optimize the best formula for Pogostone film. Methods d The membrane type and the amount of Plasticizer were determined with Dissolution and Properties of PVA; Uniform design method was used to obtain the optimal proportion of enhancers with the index of oilreleasing and with grey relational analysis, Results The best membrane type is PVA1 with 5 % of glycerin and 5 % of tween-80, the optimized combination of enhancers is A ： B ： C=6 % ： 5% ： 6 %. Conclusion The experiment could optimize the best formula for Pogostone film. The film is are reasonably designed and easily prepared. |
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| Keywords: | pogostonefilm optimization ofthe formulation memberancematerials plasticizer enhancers uniform design |
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