| Preparation and preliminary evaluation of [^55Co]（II）vancomycin |
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| 引用本文： | Amir Reza JALILIAN,Yousef YARI-KAMRANI,Pejman ROWSHANFARZAD,Mahseed SABET,Mohsen KAMALI-DEHGHAN,Abbas MAJDABADI. Preparation and preliminary evaluation of [^55Co]（II）vancomycin[J]. 核技术(英文版), 2008, 19(6) |
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| 作者姓名： | Amir Reza JALILIAN Yousef YARI-KAMRANI Pejman ROWSHANFARZAD Mahseed SABET Mohsen KAMALI-DEHGHAN Abbas MAJDABADI |
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| 作者单位： | Nuclear Medicine Research Group, Agriculture, Medicine and Industrial Research School （AMIRS）, Karaj, Iran |
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| 基金项目： | Supported partly by IAEA/IAEO research grant for cyclotron production of Co-57. |
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| 摘 要： | Co-55 (t1/2=17.53 h) was produced by 150 μA irradiation of a natural nickel target using 15 MeV protons. It was separated from the irradiated target material by two ion exchange chromatography steps with a radiochemical yield of >95% and was used for the preparation of [55Co]vancomycin ([55Co]VAN). Optimization studies were per- formed using Co-57 due to its longer half-life. Cobalt-57 (t1/2=271.79 d) was produced by irradiation of a natural nickel target with 150 μA current of 22 MeV protons. The 57Co was ...
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| 关 键 词： | 钴-55 万古霉素 医用回旋加速器 放射性同位素示踪 生物剂量学 |
Preparation and preliminary evaluation of [~(55)Co](II)vancomycin |
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| Amir Reza JALILIAN Yousef YARI-KAMRANI Pejman ROWSHANFARZAD Mahseed SABET Mohsen KAMALI-DEHGHAN Abbas MAJDABADI Nuclear Medicine Research Group,Agriculture,Medicine , Industrial Research School ,Karaj,Iran. Preparation and preliminary evaluation of [~(55)Co](II)vancomycin[J]. , 2008, 19(6) |
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| Authors: | Amir Reza JALILIAN Yousef YARI-KAMRANI Pejman ROWSHANFARZAD Mahseed SABET Mohsen KAMALI-DEHGHAN Abbas MAJDABADI Nuclear Medicine Research Group Agriculture Medicine Industrial Research School Karaj Iran |
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| Affiliation: | Amir Reza JALILIAN * Yousef YARI-KAMRANI Pejman ROWSHANFARZAD Mahseed SABET Mohsen KAMALI-DEHGHAN Abbas MAJDABADI Nuclear Medicine Research Group,Agriculture,Medicine , Industrial Research School (AMIRS),Karaj,Iran |
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| Abstract: | |
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| Keywords: | Cobalt-55 Vancomycin Medical cyclotron Radiolabeling Biodistribution |
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