初诊2型糖尿病患者踝肱指数异常率临床分析

目的研究初诊2型糖尿病（T2DM）患者中踝肱指数（ABI）异常率及影响因素。方法检测初诊T2DMABI值320例,ABI〈0.9或≥1.3为异常组（A组）,0.9〈ABI〈1.3的T2DM为正常组（B组）,比较A组与B组2组间临床代谢参数差异,分析初诊T2DM发生异常ABI的危险因素。结果 320例初诊T2DM中ABI异常者为73例（22.8%）,A组年龄、高血压病程、三酰甘油（TG）、低密度脂蛋白胆固醇（LDL-C）、糖化血红蛋白（HbA1c）、尿白蛋白（uAlb）及吸烟率明显高于B组（P〈0.05）,Binary logistic回归分析显示,年龄、uAlb为异常ABI的主要危险因素。结论初诊T2DM中异常ABI者较高,年龄、高血压病程、TG、LDL-C、HbA1c、uAlb及吸烟为异常ABI的影响因素,年龄、uAlb为影响异常ABI的主要危险因素。

Prevalence of Abnormal Ankle-brachial Index in Patients with Newly Diagnosed Type 2 Diabetes

Objective To investigate the prevalence of abnormal ankle-brachial index（ABI） in the newly diagnosed type 2 diabetic patients,and to evaluate the risk factors for abnormal ABI.Methods A total of 320 patients with newly diagnosed type 2 diabetes were divided into two groups： abnormal group（ABI0.9 or ABI≥1.3） and normal group（0.9ABI1.3）.Clinical metabolic parameters were compared between the two groups and the risk factors for abnormal ABI were analyzed.Results Seventy-three of the 320 patients（22.8%） had abnormal ABI.Compared with normal group,the age,duration of hypertension,frequency of smoking,and levels of triacylglycerol（TG）,low-density lipoprotein cholesterol（LDL-C）,glycated hemoglobin（HbA1c） and urinary albumin（uAlb） significantly increased in abnormal group.Binary logistic regression analysis showed that the age and uAlb were the independent risk factors for abnormal ABI.Conclusion Patients with newly diagnosed type 2 diabetes have a high prevalence of abnormal ABI.The age,duration of hypertension,TG,LDL-C,HbA1c,uAlb and smoking（especially the age and uAlb） were the risk factors for abnormal ABI.