| 冻干麻疹活疫苗有效期的考查 |
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| 引用本文： | 张守德,孙金华,姜景芝.冻干麻疹活疫苗有效期的考查[J].粉末涂料与涂装,1992(1). |
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| 作者姓名： | 张守德 孙金华 姜景芝 |
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| 作者单位： | 卫生部长春生物制品研究所，卫生部长春生物制品研究所，白求恩医科大学第一临床学院 长春 130062，长春 130062 |
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| 摘 要： | 随机抽取12批冻干麻疹活疫苗,保存于4～10℃,48～50个月后其毒力滴度100％合格(2.5 LogTCID_(50))。在保存26个月的疫苗中,随机抽取4批接种22名易感儿,抗体100％阳转。未见异常反应。根据疫苗的稳定性及人体免疫效果可考虑适当延长疫苗效期。
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| 关 键 词： | 冻干麻疹活疫苗 稳定性 免疫效果 |
Preliminary Study on the Stability of Freeze-dried Measles Vaccine within the Alloted Time |
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| Zhang Shoude et al Changchun Institute of Biological Products,Changchun.Preliminary Study on the Stability of Freeze-dried Measles Vaccine within the Alloted Time[J].Chinese Journal of Biologicals,1992(1). |
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| Authors: | Zhang Shoude Changchun Institute of Biological Products Changchun |
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| Abstract: | 12 lots of freeze-dried measles vaccine randomly selected were stored for 48-50 months, and the titer of the vaccine is up to standard(2.5 log) by 100%. 22 susceptible subjects were vaccinated with the 4 lots of randomly selected vaccine that had been stored for 26 months,and their HI antibody positive rates were 100 %, no abnormal reaction occured. According to the stabillty and the immunizing potency of the vaccine, it is thought that the expiry date of the ferrze-dried measles vaccine conld be prolonged for 1-2 vears properly. |
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| Keywords: | Freeze-dried Measled Vaccine Stabilit y Immunizing potency |
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