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Fatty Acid Synthesis in Glial Cells of the CNS
Authors:Aida V. Garcia Corrales  Mansour Haidar  Jeroen F. J. Bogie  Jerome J. A. Hendriks
Affiliation:Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, 3590 Diepenbeek, Belgium; (A.V.G.C.); (M.H.); (J.F.J.B.)
Abstract:Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pathologies such Alzheimer’s disease or multiple sclerosis. Intervention strategies targeting FA synthesis in glia represents a potential therapeutic opportunity for several CNS diseases.
Keywords:fatty acids   glia   central nervous system   neurological disease   CNS repair
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