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硅藻土特性、提纯及在生物医药领域中的应用
引用本文:张育新, 戴兴健, 张臣智, 张欣芳, 易志宇, 杜智岚, 周权. 硅藻土特性、提纯及在生物医药领域中的应用[J]. 矿产保护与利用, 2021, 41(6): 46-56. doi: 10.13779/j.cnki.issn1001-0076.2021.06.006
作者姓名:张育新  戴兴健  张臣智  张欣芳  易志宇  杜智岚  周权
作者单位:重庆大学 材料科学与工程学院, 重庆 400044
基金项目:滨海工程混凝土锈蚀智能抑制系统U1801254
摘    要:基于生物纳米材料的药物和设备在精准治疗和个性化治疗方面具有广阔的应用前景。硅藻土作为战略性非金属矿产,其高比表面积、生物相容性、易于表面修饰、热稳定性、高机械和化学抗性以及低成本的特性,使硅藻土在生物医学应用方面具有极大的潜力。介绍了硅藻土材料的结构、表面化学功能化、生物相容性等特性,综述了硅藻土在生物医学领域的药物传递、生物传感、组织工程和止血剂等方面的应用。

关 键 词:硅藻土   特性   提纯   生物医药   药物载体   纳米材料   生物传感
收稿时间:2021-10-08

Research Progress on The Properties of Diatomite and Its Application in Biomedical Field
ZHANG Yuxin, DAI Xingjian, ZHANG Chenzhi, ZHANG Xinfang, YI Zhiyu, DU Zhilan, ZHOU Quan. Research Progress on The Properties of Diatomite and Its Application in Biomedical Field[J]. Conservation and Utilization of Mineral Resources, 2021, 41(6): 46-56. doi: 10.13779/j.cnki.issn1001-0076.2021.06.006
Authors:ZHANG Yuxin  DAI Xingjian  ZHANG Chenzhi  ZHANG Xinfang  YI Zhiyu  DU Zhilan  ZHOU Quan
Affiliation:Chongqing University, College of Materials Science and Engineering, Chongqing 400044, China
Abstract:Drugs and devices based on bio-nanomaterials have promising applications in precision and personalized therapy. Diatomite, as a strategic nonmetallic mineral, has great potential for biomedical applications due to its high specific surface area, biocompatibility, ease of surface modification, thermal stability, high mechanical and chemical resistance, and low cost. The structural properties, purification, surface chemical functionalization, and biocompatibility of diatomite materials are presented, and the applications of diatomite in biomedical fields such as drug delivery, biosensing, tissue engineering, and hemostatic agents are reviewed. 
Keywords:diatomite  biopharmaceuticals  drug carriers  nanomaterials  biosensing
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