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Strained Dehydrogenative Ring Closure of Phenylcarbazoles
Authors:Alexander W. Jones  Marie‐Laure Louillat‐Habermeyer  Frederic W. Patureau
Abstract:What does it take to force a rigid and strained dehydrogenative ring closure, for example, in phenylcarbazoles? Since the works of Buchwald and Fagnou, palladium‐catalysed ring‐closing dehydrogenative reactions are legion, but will not operate when the strain at the reductive elimination stage becomes too large. We propose here a “muscled up” super‐oxidative palldium‐catalysed C H activation method for the ring closure of strained phenylcarbazoles.
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Keywords:C?H activation  cooperative oxidation  dehydrogenative cyclisation  palladium  strained reductive elimination
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