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Gold‐Catalyzed Synthesis of 3‐Acylimidazo[1,2‐a]pyridines via Carbene Oxidation
Authors:Haiying Zhan  Limin Zhao  Jinqiang Liao  Naiying Li  Qinlin Chen  Shuxian Qiu  Hua Cao
Abstract:A convenient gold‐catalyzed strategy for the synthesis of imidazo[1,2‐a]pyridine derivatives has been developed via gold carbene complexes. This transformation opens a new synthetic route to a variety of 3‐carbonyl‐substituted imidazo[1,2‐a]pyridines using air as oxidant affording the products in good yields.
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Keywords:carbene oxidation  gold catalysis  imidazo[1,2‐a]pyridines  propiolaldehyde  pyridin‐2‐amines
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