Structure of D-amino acid oxidase: new insights from an old enzyme |
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Authors: | A Mattevi MA Vanoni B Curti |
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Affiliation: | Dipartimento di Genetica e Microbiologia, Università di Pavia, Italy. mattevi@ipvgen.unipv.it |
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Abstract: | D-amino acid oxidase is the prototype of flavin-dependent oxidases. The recent resolution of its 3D structure has provided an explanation for several of its properties and has led to a substantial revision of the mechanism of D-amino acid dehydrogenation, with significant implications for the general understanding of flavin-dependent catalysis. |
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