| 基于HH模型的心肌细胞电模型 |
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| 引用本文： | 张莹,李智. 基于HH模型的心肌细胞电模型[J]. 计算机与数字工程, 2012, 40(4): 1-2,5 |
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| 作者姓名： | 张莹 李智 |
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| 作者单位： | 四川大学电子信息学院 成都 610065 |
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| 摘 要： | 提出了一种心肌细胞电生理模型的建模仿真方法。通过借助Hodgkin-Huxley模型对单个心肌细胞建立细胞膜的等效电路模型,利用四阶Rouge-Kutta算法,研究并分析了心肌细胞膜内外离子电流及电位差变化。然后用C语言完成了对细胞膜等效电路模型的编程,利用Matlab软件平台进行了计算机仿真,得到了心肌细胞电生理学模型在不同刺激下的仿真实验结果。
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| 关 键 词： | 心肌细胞 电生理模型 Hodgkin-Huxley模型 Rouge-Kutta算法 |
Electric Model of the Myocardial Cell Based on Hodgkin-Huxley Model |
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| ZHANG Ying , LI Zhi. Electric Model of the Myocardial Cell Based on Hodgkin-Huxley Model[J]. Computer and Digital Engineering, 2012, 40(4): 1-2,5 |
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| Authors: | ZHANG Ying LI Zhi |
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| Affiliation: | (Department of Electronics and Information Engineering,Sichuan University,Chengdu 610065) |
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| Abstract: | A modeling and simulation methods of electrophysiological model of myocardial cells were proposed.Based on the Hodg-kin-Huxley model,equivalent circuit model of the rat’s single cardiac muscle cell was built.Using fourth-order Rouge-Kutta algorithm,internal and external cardiac membrane ionic current and potential difference changes has been researched and analyzed.Making use of C Language,the program of the cardiac cell membrane was realized like equivalent circuit model,and the computer’s simulation through Mat-lab software platform was realized.As a result,it obtained the result of simulation experience of electrophysiological model of cardiac muscle cell under every different kinds of stimulation. |
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| Keywords: | cardiac muscle cell electrophysiological model Hodgkin Huxley model Rouge-Kutta algorithm |
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