In vitro study on porous silver scaffolds prepared by electroplating method using cellular carbon skeleton as the substrate |
| |
Authors: | M. Guo X. Wang H.M. Zhou L. Li F.L. Nie Y. Cheng Y.F. Zheng |
| |
Affiliation: | 1. Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin 150001, China;2. Department of Advanced Materials and Nanotechnology, College of Engineering, Peking University, Beijing 100871, China;3. Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China |
| |
Abstract: | Porous silver scaffolds, with the porosity ranging from 68% to 81% and the apparent density ranging from 0.4 to 1 g?cm? 3 were prepared by electroplating method using cellular carbon skeleton as the substrate. The microstructure, mechanical property, cytotoxicity and antibacterial activity of the prepared porous silver scaffold were studied. The present porous silver scaffolds had a highly three-dimensional trabecular porous structure with the porosity and the apparent density close to that of the cancellous bone. Furthermore, the mechanical property such as elastic modulus and yield strength of the porous silver scaffolds were lower than that of commercial available porous Ti and porous Ti alloys but much closer to that of the cancellous bone and porous Ta. In addition, study of in vitro behavior showed that the porous silver scaffold possessed significant antibacterial capability of inhibition of bacterial proliferation and adherence against Staphylococcus aureus and Staphylococcus epidermidis, and little cytotoxicity to Mg-63 cell line and NIH-3T3 cell line. Consequently, the porous silver scaffolds prepared by electrodeposition possess a promising application for bone implants. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|