| 等离子体处理乙丙交酯共聚物表面固定胶原的研究 |
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| 引用本文： | 崔媛,段潜,李艳辉.等离子体处理乙丙交酯共聚物表面固定胶原的研究[J].材料工程,2011(6):58-62. |
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| 作者姓名： | 崔媛 段潜 李艳辉 |
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| 作者单位： | 长春理工大学; |
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| 基金项目： | 国家自然科学基金资助项目(50903009); 吉林省科技发展计划项目(20100115) |
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| 摘 要： | 选择等离子体对乙丙交酯共聚物(PLGA)表面进行活化处理来接枝胶原.通过测定等离子体处理后PLGA材料表面水接触角确定最佳处理功率为60W,时间5min.XPS分析确定胶原表面的羧基与PLGA表面等离子体激活的羟基发生了反应生成酯基,而使胶原接枝到PLGA表面.选用小鼠胚胎内皮成纤维细胞(3T3)在PLGA材料表面培养...
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| 关 键 词： | PLGA 等离子体 胶原 |
Investigation of Plasma Treatment and Collagen Immobilization on the Surface of Poly(lactid-glycolide acid) |
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| CUI Yuan,DUAN Qian,LI Yan-hui.Investigation of Plasma Treatment and Collagen Immobilization on the Surface of Poly(lactid-glycolide acid)[J].Journal of Materials Engineering,2011(6):58-62. |
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| Authors: | CUI Yuan DUAN Qian LI Yan-hui |
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| Affiliation: | CUI Yuan,DUAN Qian,LI Yan-hui(Changchun University of Science and Technology,Changchun 130022,China) |
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| Abstract: | For collagen is a major component of the extracellular matrix,when the surface of poly(lactid-glycolide acid)(PLGA) is grafted with collagen,cytocompatibility of PLGA will be improved.Plasma treatment is selected to immobilize collagen on the surface of PLGA.Optimum power and treating time of plasma are determined by contact angle test.The results indicate they are 60W and 5min,respectively.XPS analysis reveals that carboxy groups on collagen are reacted with actived hydroxyl groups on the surface of plasma... |
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| Keywords: | PLGA plasma collagen |
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