The effect of superhigh doses of gamma radiation on the energetics of rat liver mitochondria

The effect of high dose of gamma radiation (200 Gy) on energy of rat liver mitochondria was studied. 1 hour after irradiation state 3 (V3) increased by 32 +/- 7%, state 4 (V4)- by 25 +/- 8%, the rate of ATP synthesis by 52 +/- 11%. 48 hours after irradiation these parameters decreased to control levels inspite of accumulation of lipid peroxidation products.