Self-Optimizing Reactor Systems: Algorithms,On-line Analytics,Setups, and Strategies for Accelerating Continuous Flow Process Optimization |
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Authors: | David C Fabry Erli Sugiono Magnus Rueping |
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Affiliation: | Institute of Organic Chemistry, RWTH-Aachen University, Landoltweg 1, 52074 Aachen (Germany) phone: +49-(0)241-8094710 fax: +49-(0)241-8092665 |
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Abstract: | This review provides an overview of recent developments in the area of continuous flow process optimization by employing self-optimizing reactor systems. Although only few reactor concepts have been realized to date, impressive progress has been made, which now allows fully automated reaction optimization without the need of human interactions. |
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Keywords: | asymmetric reduction cross-coupling hydrogenation microreactor Suzuki reaction |
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