The statistical power and biological information of two Daphnia juvenile production test designs |
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| Affiliation: | 1. Biometeorology and Soil Physics Group, University of British Columbia, Vancouver, Canada;2. Canadian Forest Service, Northern Forestry Center, Edmonton, Canada;1. Veolia Recherche et Innovation, Chemin de la digue, BP 76, 78603 Maisons-Laffitte Cedex, France;2. UMR HydroSciences 5569, Faculté de Pharmacie, 15 Avenue Ch. Flahault, 34093 Montpellier Cedex 5, France;1. State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, CAS, 830011 Urumqi, China;2. Cele National Station of Observation and Research for Desert-Grassland Ecosystems, 848300 Cele, China;3. Department of Applied Plant Science, Chonnam National University, 500757 Gwangju, South Korea;4. Department of Ecosystem Physiology, University of Freiburg, 79085 Freiburg, Germany;5. Department of Plant Ecology, BayCEER, University of Bayreuth, 95447 Bayreuth, Germany |
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| Abstract: | This paper examines the statistical power for two designs of Daphnia chronic toxicity test, one (the “old” OECD method) using four groups of 10 animals at each treatment, the other (the “new” OECD method) using 10 individually housed animals at each treatment. Both use reproduction as the end point. It was demonstrated during a pilot ring test of the new method, run concurrently with the old method, that their statistical powers were similar. The old method had a power for detecting a 20% real difference of 0.97, while the power of the new method was 0.90. These findings are reported, together with observations on the quality of data that may be obtained using the different test designs. It is suggested that the new design may be of use in investigating toxicological modes of action, in view of the improved data capture that it allows. |
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