Aptatag‐Based Multiplexed Assay for Protein Detection by Surface‐Enhanced Raman Spectroscopy |
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| Authors: | Laura Fabris Martin Schierhorn Martin Moskovits Guillermo C. Bazan |
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| Affiliation: | 1. Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106 (USA);2. Current address: Department of Materials Science and Engineering and Institute for Advanced Materials Devices and Nanotechnology Rutgers, The State University of New Jersey Piscataway, NJ 08854 (USA);3. Department of Materials Center for Polymers and Organic Solids University of California Santa Barbara, CA 93106 (USA) |
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| Abstract: | Silver‐nanoparticle dimers held together by a Raman reporter, capped with DNA aptamers and stabilized by polyethylene glycol chains, can be used to develop a multiplexed heterogeneous bioassay for protein detection with high sensitivity and selectivity. |
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| Keywords: | aptamers bioassays nanoparticles proteins Raman spectroscopy |
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