Pathologic classification of prostate carcinoma: the impact of margin status

Analysis of experimental data demonstrates that cosmic ray enhancement stimulates an increase of atmospheric aerosols and cloudiness. The study of solar proton events (SPE) has shown that during SPE one can observe increase in aerosol density by 1.2-1.4 times at 12-18 km altitudes. Such variations of aerosol density can be detected on global scale. Aerosol variations cause changes in integral atmospheric transparency which during disturbed periods can reach 5-6%. The atmospheric integral transparency variations are not less during the solar cycle on account of galactic cosmic ray variations. Atmospheric transparency variations creating the so-called "grey filter" for solar radiation should lead to surface temperature variations. During the periods of low solar activity under the influence of enhanced galactic cosmic ray fluxes, the density of the "grey filter" should increase and cause a decrease in surface temperatures, correspondingly. In frame of the physical mechanism considered the connection between solar cycle durations and surface temperature variations can be explained. In addition, one can understand the physical reason for the "Little Ice Age" appearance during Maunder minimum of solar activity, 2400 years periodicity of climatic processes, strong influence of the decrease in main geomagnetic field intensity on the development of Ice Age and Global Cooling.