分散固相萃取-超高效液相色谱-串联高分辨质谱法测定新疆苹果中7 种农药残留

为快速得到新疆苹果中痕量农药信息，考察新疆苹果种植过程中常用的7?种农药，并针对这7?种常见农药建立了分散固相萃取-超高效液相色谱-串联高分辨质谱的分析方法，旨在快速筛查出可能的农药并同时定量。结果表明：7?种农药线性关系良好，相关系数均大于0.99。方法检出限为0.003～0.1?mg/kg，定量限为0.02～0.5?mg/kg，平均回收率为95%～119%之间，相对标准偏差小于10%（n＝3）。该方法能够排除假阳性结果，快速高效地完成出口前新疆苹果中多农药残留的分析。

Determination of 7 Pesticide Residues in Xinjiang Grown Apple by Dispersive Solid-Phase Extraction Combined with Ultra Performance Liquid Chromatography-High Resolution Tandem Mass Spectrometry

To quickly obtain information about trace pesticides in Xinjiang grown apple, we investigated 7 commonly used pesticides during apple planting, and established a dispersive solid phase extraction combined with ultra performance liquid chromatography-high resolution tandem mass spectrometry (UPLC-HRMS/MS) method to quickly screen and quantitatively analyze the target pesticides. The results showed that good linearity was observed for all 7 analytes with correlation coefficients above 0.99. The limits of detection (LODs) were in the range of 0.003–0.1 mg/kg and the limits of quantification (LOQs) ranged between 0.02 and 0.5 mg/kg. Average recoveries were in the range of 95%–119% with relative standard deviation (RSD) less than 10% (n = 3). The method allowed for the rapid multi-residue analysis of pesticides in Xinjiang grown apples to be exported without any false-positive results.