Highly regioselective palladium-catalyzed direct cross-coupling of imidazo[1,2-a]pyridines with arylboronic acids |
| |
| Affiliation: | 1. School of Chemistry and Chemical Engineering, the Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, Shihezi University, Shihezi City 832004, China;2. Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, Hubei Key Laboratory of Material Chemistry and Service Failure, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, 1037 Luoyu road, Hongshan District, Wuhan 430074, China;3. Laboratory of Green S.O.C. –Dipartimento di Chimica, biologia e Biotecnologie, Università degli Studi di Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy;1. Ministry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry, College of Chemistry & Materials Science, Northwest University, Xi''an 710127, China;2. Lab of Tissue Engineering, Provincial Key Laboratory of Biotechnology of Shaanxi, Ministry of Education Key Laboratory of Resource Biology and Modern Biotechnology, The College of Life Sciences, Faculty of Life and Health Science, Northwest University, Xi''an 710127, China;3. Fluorescence Research Group, Singapore University of Technology and Design, Singapore 487372, Singapore |
| |
| Abstract: | A highly regioselective method for the palladium-catalyzed direct cross-coupling of imidazo1,2-a]pyridines with arylboronic acids has been developed by using O2 as oxidant. This process can be applied to a wide range of imidazo1,2-a]pyridines and arylboronic acids with excellent C-3-regioselectivity. It provides a new way for developing C C bond-forming processes of multisubstituted imidazo1,2-a]pyridines, which are common structural motifs in natural products and pharmaceuticals. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
